Location: Route 157 and St. Clair Ave, East St Louis Stay straight for 157 north after the 161 junction. Location: Route 157 and St. Clair Ave, East St Louis Reassurance shield after the 161 junction. Location: Route 157 and Tucker Dr, Caseyville A couple miles later, we’ll approach Interstate 64. Location: Route 157 and Tucker … Continue reading Illinois Route 157, IL-161 to I-64/US-50